hyaluronic acid

noun

hy·​al·​uron·​ic acid ˌhī(-ə)l-yu̇-ˈrä-nik 

: a viscous glycosaminoglycan chiefly of the matrix of tissues that occurs especially in the vitreous humor, umbilical cord, synovial fluid, and loose connective tissue and serves especially as a structural element and lubricant

Examples of hyaluronic acid in a Sentence

Recent Examples on the Web

The formula is packed with hyaluronic acid to deeply hydrate and plump the skin, and it can be applied on its own or mixed into a moisturizer. —Alanna Martine Kilkeary, Glamour, 10 Apr. 2025

The best sheet masks are more than just selfie material—they’re serious skin-care products designed to hug your face, soothe your skin, and deliver high concentrations of potent ingredients like hyaluronic acid, niacinamide, snail mucin, and retinol. —Annie Blackman, Allure, 10 Apr. 2025

Sodium hyaluronate, a derivative of hyaluronic acid, is the star ingredient paired with glycerin and vitamin E to help skin retain moisture, minimize fine lines, and quell dryness. —Kiana Murden, Vogue, 8 Apr. 2025

However, for additional beauty benefits and boosted cellular health, the brand’s unflavored powder also includes vitamin C, hyaluronic acid and nicotinamide riboside, a precursor to longevity coenzyme NAD+. —Emily Burns, Footwear News, 1 Apr. 2025

Word History

Etymology

International Scientific Vocabulary

First Known Use

1934, in the meaning defined above

Rhymes for hyaluronic acid

• antacid
• placid

Medical Definition

hyaluronic acid

noun

hy·​al·​uron·​ic acid ˌhīl-yu̇-ˌrän-ik-  ˌhī-əl-yu̇- 

: a viscous glycosaminoglycan that occurs especially in the vitreous body, the umbilical cord, and synovial fluid and as a cementing substance in the subcutaneous tissue